RADIESSE® Collagen Stimulator

Collagen and elastin are two naturally occurring proteins that give volume, flexibility, and strength to the skin. As we age, collagen and elastin break down, diminishing facial volume and elasticity, resulting in the development of wrinkles, facial lines, and skin laxity. Replenish lost collagen, restore skin health, and refresh your appearance with RADIESSE®, the first FDA-approved cosmetic filler for revitalizing the appearance of both the face and hands, from a dermatologist in Gainesville with Gainesville Dermatology Aesthetic Center.

Contact us today to find out more about our encompassing range of skin care treatments and to schedule RADIESSE® treatments.


Ideal wrinkle reduction and skin plumping are achieved by replenishing the skin’s lost volume. The RADIESSE® filler is a cosmetic dermal filler used for smoothing moderate-to-severe facial wrinkles and folds, such as the creases that extend from the corner of your nose to the corner of your mouth (nasolabial folds). RADIESSE® is also used for correcting volume loss in the back of the hands. Upon injection, RADIESSE® immediately provides the volume and lift needed to diminish the signs of aging due to the formulation’s microspheres, which are mainly composed of calcium hydroxylapatite (a mineral present in the bones) and gel. This collagen stimulator uniquely acts as scaffolding under the skin, creating structure and stimulating collagen in the skin. Contact us to learn more about RADIESSE® and find out how our available cosmetic fillers can help you achieve your aesthetic goals.

What Is RADIESSE® Used For?

RADIESSE® facial filler is a thick dermal filler made of calcium-based microspheres suspended in a water-based gel and is used to help visibly plump wrinkled or folded areas of the skin, most often in the face. It is an excellent choice for facial contouring and for correcting asymmetries in the face. As with hyaluronic acid fillers, such as JUVÉDERM® and Restylane®, RADIESSE® can help soften lines of the nasolabial folds and smooth marionette lines. However, this product is especially effective in contouring the cheeks, chin, and jawline, which can likewise help boost wrinkle reduction and softening of nasolabial folds. One of the most common uses of this filler is volumizing sunken cheeks for a more youthful appearance. The following comprises some of the most common uses of RADIESSE®.

  • Adding volume to sunken temples
  • Non-surgical nose reshaping
  • Lifting, volumizing, and contouring cheeks
  • Smoothing nasolabial folds
  • Defining and shaping the jawline
  • Softening marionette lines
  • Volumizing jowls and drooping cheeks
  • Adding volume to areas on the back of the hands


Both RADIESSE® and JUVÉDERM®, which includes JUVÉDERM® XC and JUVÉDERM Voluma® XC, are dermal fillers that can add desired fullness to the face. There is no one-size-fits-all option regarding which facial filler to choose, as the choice really depends on the individual’s facial features and which areas the client seeks to treat. RADIESSE® is an excellent choice for smoothing and filling out moderate-to-severe folds and creases in the skin, while JUVÉDERM® XC is optimal for adding volume to facial areas.

Due to its thick composition of calcium hydroxylapatite microspheres, RADIESSE® is preferred by those desiring a smoother skin surface where marionette lines and deeper creasing exist. JUVÉDERM®, alternatively, comprises a thin gel with a concentrated amount of hyaluronic acid present, which, when injected beneath the skin, is drawn in and holds moisture, creating a slight plumping effect. As such, JUVÉDERM® is an excellent choice for plumping thinning lips as well as reducing creases around the eyes and small wrinkle lines around the corners of the mouth.

Am I A Good Candidate For RADIESSE®?

RADIESSE® is both safe and effective for the vast majority of patients. Virtually any patient with volume loss in the face or hands is a candidate for treatment with RADIESSE®, as well as those with poorly defined cheekbones, and patients seeking definition in their chin, temples, or jaw. RADIESSE® is an overall versatile dermal filler that can be beneficial for treating many different areas. Individuals with significant skin laxity and volume loss tend to benefit most from treatment with facial fillers, such as RADIESSE®. The best way to determine whether or not you are a candidate for cosmetic fillers is to speak with a Gainesville dermatologist with our practice. Contact us today to discuss your cosmetic goals and treatment plan. Patients with the following conditions should not use RADIESSE®.

  • History of severe allergies
  • Allergy to gram-positive bacteria
  • Allergic reactions to cosmetic fillers
  • Bleeding disorders
  • Allergy to anesthetics, such as lidocaine
  • Patients who are pregnant or breastfeeding


Treatment with RADIESSE® typically takes about 30 minutes per session in our office. A topical or injected anesthetic may be provided immediately before the procedure to minimize any discomfort. Once the targeted area is prepared for treatment, RADIESSE® is injected through a tiny needle into the skin. Several injections may be required, depending on the size and scope of the treatment area as well as the patient’s desired result. RADIESSE® is highly unique in its ability to enhance the skin’s condition both short term and long term. In the short term, patients who receive RADIESSE® notice a supported framework beneath the skin, which immediately and visibly restores depleted facial volume. In the long term, RADIESSE® supercharges the body’s natural production of collagen, which hydrates the skin and creates marked plumpness, elasticity, and firmness in the treated areas.

How Long Does RADIESSE® Last?

The ingredients in RADIESSE® are not easily or quickly broken down by the body. As a result, RADIESSE® is one of the longest-lasting injectable fillers currently available. Medical studies using both ultrasound and MRI imaging demonstrate that RADIESSE® produces a long-lasting and dense collagen matrix, which supports improved mechanical properties of the skin. The lasting-power of RADIESSE® can vary from patient to patient, however, results typically last 9-15 months, after which point the patient may require additional treatment to maintain the desired results. Contact us to learn more about our available injectables and to schedule a consultation for treatment with RADIESSE®.

What Are The Side Effects Of RADIESSE®?

The majority of patients who receive treatment with this facial filler experience no adverse side effects. However, potential side effects following injection can include bruising, redness, swelling, pain, itching, nodules or bumps/lumps, difficulty performing activities, loss of sensation, and other local side effects. The most common adverse events seen in clinical studies of RADIESSE® used in the face include bruising, redness, swelling, pain, itching, and other local side effects. For more information about possible side effects of treatment and to learn about pre- and post-treatment recommendations for care, contact our office.